More than 600 NPW-registered schemes are eligible to enter the event, which is now in its fourth year.
The winners will be selected by a panel of NPW members and industry experts at an awards ceremony and dinner held at the House of Commons this Autumn.
Last year the Droylsden scheme in Manchester lifted the national accolade.
Andrew Cowan, country director, Diageo GB, claimed the scheme was established under "very difficult circumstances" but became a "uniting force for local licensees" resulting in an excellent working relationship with Greater Manchester Police.
“Winning the 2014 award meant so much to us, and it is fantastic to have been recognised for the effort we have put in, but also for the town as a whole,” Alan Graham, chairman of the Pubwatch scheme said.
“People are still stopping us whilst out and about to say ‘well done, it’s about time all the pubs worked together’. We have had lots of positive comments from the public since winning the award and recognition that we are working to make our community a safer place”.
In an open letter, Cowan added: “Droylsden is a fantastic example of an outstanding Pubwatch scheme, but we know great work is being done by many other local schemes around the UK. I would like to encourage you to take the opportunity to enter the National Pubwatch Awards and tell us about the work you have done in your area.”
Applicants have until the 17 July to enter and can do so online via the Pubwatch Awards section of the NPW site.